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Investigational approaches include cryotherapy, methylaminolevulinic acid‐based photodynamic therapy, topical calcineurin inhibitors (CNIs), topical prostaglandin analogs (e.g., latanoprost or bimatoprost), pulsed infrared diode laser therapy, and antihistamines [25, 26]
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Cortisol Awakening Response (CAR) – Measures the cortisol increase just after waking, and helps to assess HPA axis dysfunction and stress resilience through the day
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